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Click HERE for the complete PubMed listing of publications by Michael J. Eck

Selected recent papers (with links):

Lietha D, Cai X, Ceccarelli DF, Li Y, Schaller MD, Eck MJ. (2007) Structural basis for the autoinhibition of focal adhesion kinase. Cell 129, 1177-1187.

Lu J, Meng W, Poy F, Maiti S, Goode BL, Eck MJ. (2007) Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly. J Mol Biol 369, 1258-1269.

Goode BL, Eck MJ. (2007) Mechanism and function of formins in the control of actin assembly. Annu Rev Biochem 76, 593-627.

Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, Meyerson M, Eck MJ. (2007) Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell 11, 217-227.

Nezami AG, Poy F, Eck MJ. (2006) Structure of the autoinhibitory switch in formin mDia1. Structure 14, 257-263.

Boggon TJ, Li Y, Manley PW, Eck MJ. (2005) Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog. Blood 106, 996-1002.

Xu Y, Moseley JB, Sagot I, Poy F, Pellman D, Goode BL, Eck MJ. (2004) Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture. Cell 116, 711-723.

Kim PW, Sun ZY, Blacklow SC, Wagner G, Eck MJ. (2003) A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8. Science 301, 1725-1728.